COVID-19 infections are surging again in the U.S., despite the availability of vaccines that are both safe and effective. In the inaugural episode of the GSAS Colloquy podcast, alumnus Michael Lin, a microbiologist and Professor at Stanford University talks about vaccination mandates as a path out of the pandemic, but also about the decline in vaccine efficacy over time. He advocates booster shots for adults over the age of 16, as well as continued public health measures like masking indoors. Lin also speaks about ongoing work at his lab to develop a new treatment for COVID-19 that targets the virus on the molecular level.